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Paroxetine
CAS number 61869-08-7
Paroxetine Formula C19H20FNO3

Paroxetine is a selective serotonin reuptake inhibitor (SSRI) antidepressant.

Paroxetine is primarily used to treat the symptoms of major depression, obsessive-compulsive disorder (OCD), post-traumatic stress disorder (PTSD), panic disorder, generalized anxiety disorder (GAD), social phobia/social anxiety disorder, and premenstrual dysphoric disorder (PMDD).

Systematic (IUPAC) name
(3S,4R)- 3-([benzo[d] [1,3]dioxol-5-yloxy] methyl)- 4-(4-fluorophenyl) piperidine
Identifiers

ATC code N06AB05
PubChem 43815
DrugBank APRD00364
ChemSpider 39888
Chemical data
Formula C19H20FNO3
Mol. mass 329.3
SMILES eMolecules & PubChem
Pharmacokinetic data
Bioavailability Completely absorbed from GI, but extensive first-pass metabolism in the liver; Tmax 4.9 (with meals) to 6.4 hours (fasting)
Protein binding 93–95%
Metabolism Extensive, hepatic (mostly CYP2D6-mediated)
Half life 24 hours (range 3–65 hours)
Excretion 64% in urine, 36% in bile
Therapeutic considerations
License data
Pregnancy cat.
Legal status
Prescription only
Routes Oral

Information Associated with Product:

DRUG DESCRIPTION

DOSAGE

SIDE EFFECTS

PRECAUTIONS

INTERACTION

CONSUMER INFORMATION

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	Chemicals
	Ethanol
	Phenyl acetic acid
	3,4-methylenedioxyphenyl-2-propanone
	Pseudoephedrine
	Piperidine
	Methylamine
	Propionic anhydride
	Para Methoxy Phenyl Acetone
	Para Methoxy Phenyl Acetic Acid
	Raspberry Ketone
	Benzyl Acetone
	Tyramine
	Biphenyl (Phenyl benzene)
	1-phenyl-1-hexanone
	Benzene
	Benzyl methyl ketone
	Bromo phenyl acetone (1-Bromo-1-phenyl-2-propanone)
	3'-Aminoacetophenone
	3'-Chloroacetophenone
	Toluene
	Denatonium Benzoate
	Anthranilic acid
	Ephedrine
	Ergonovine
	Ergotamine
	Hydroiodic
	Norpseudoephedrine
	Phenylpropanolamine
	Phosphorus
	Benzaldehyde
	Nitroethane
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	Ethylamine
	Isosafrole
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	Piperonal
	N-methylephedrine
	N-methylpseudoephedrine
	Acetic anhydride
	Diethyl ether
	Potassium permanganate
	2-butanone
	Toluene
	Potassium permanganate
	2-butanone
	Methyl isobutyl ketone
	Hydrochloric acid
	Para Anisyl Choride
	Para Anisic Acid
	Para Anisyl Bromide
	Para Anisoyl Acetone
	Methyl Tyramine
	Tyramine
	Para Cresyl Acetate
	Para Cresyl Methyl Ether
	Anisyl Formate
	Ortho Anisic Aldehyde
	3-Aminopropyl Imidazole
	3-Benzyloxy Propionitrile
	1-Hydroxy Cyclohexyl-4-Methoxyphenylacetonitrile
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