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3-Chloroacetophenone
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IUPAC Name:
1-(3-chlorophenyl)ethanone
Synonyms:
3'-Chloroacetophenone, omega-Chloroacetophenone,CHLOROACETOPHENONE,
Ambap7200, Acetophenone, 3'-chloro-, Ethanone, 1-(3-chlorophenyl)-,
1-(3-Chlorophenyl)ethanone, CCRIS 638, 288799_ALDRICH, 22845_FLUKA,
EINECS 202-721-8, ZINC02039606, Ethanone, 1-phenyl-, monochloro
deriv, Ethanone, 1-phenyl-, monochloro deriv., LS-67567, InChI=1/C8H7ClO/c1-6(10)7-3-2-4-8(9)5-7/h2-5H,1H,
99-02-5, 1341-24-8, 29731-15-5
CAS Registry Number: 99-02-5
Molecular Formula: C8H7ClO
Molecular Weight: 154.593580 [g/mol]
Density 1.184
Boiling point 241 ºC
Flash point 105 ºC |
Other chemicals were found as well:
chlorodiphenyl (which can cause liver damage and irritate the eyes and
skin), chloroacetophenone (tear gas), phosgene (a colorless gas that can
cause weakness lasting weeks or months), hydrogen cyanide (a colorless
gas with a slight almond-like odor that at low-level exposures can cause
breathing difficulties, heart pains, vomiting, and headache), and
trichloroarsine (which affects respiration and can cause cancer).
Phenacyl chloride is a substituted acetophenone. It is a useful building
block in organic chemistry. Apart from that, it has been historically
used as a riot control agent, where it is designated CN.
Preparation
Phenacyl chloride is readily available commercially. It may be
synthesized by the Friedel-Crafts acylation of benzene using
chloroacetyl chloride, with an aluminium chloride catalyst
Uses
* 3-Chloroacetophenone is primarily used as a riot-control agent (tear
gas) and in Chemical Mace. (1-3,7)
* It is also used as a pharmaceutical intermediate and formerly as an
alcohol denaturant.
Sources and Potential Exposure
* The use of tear gas and Chemical Mace to control riots and disable
attackers causes direct exposure to 3-Chloroacetophenone through skin
contact and inhalation.
Occupational exposure may occur during its manufacture and use by
inhalation and dermal contact.
Assessing Personal Exposure
* No information was located regarding the measurement of personal
exposure to 3-Chloroacetophenone.
Health Hazard Information
Acute Effects:
* 3-Chloroacetophenone is a potent eye, throat, and skin irritant. Acute
inhalation exposure of humans causes burning of the eyes with
lacrimation; some degree of blurred vision; possible corneal damage;
irritation and burning of the nose, throat, and skin; burning in the
chest with dyspnea; and laryngotracheobronchitis
Acute dermal exposure is irritating and can result in first, second, and
third degree chemical burns in humans; these effects are exacerbated
when the skin is wet. Acute animal tests in rats, mice, rabbits, and
guinea pigs have demonstrated 3-Chloroacetophenone to have high acute
toxicity from oral exposure.
 Note:
These API/ chemicals are designated as
those that are used in the manufacture of the controlled substances and
are important to the manufacture of the substances. For any (Control
Substance) products Import and Export *** subjected to your country
government laws /control substance ACT.
Note /Government Notification:
N/A
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India
