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Each film-coated tablet contains
Composition
Levonorgestrel I.P....................................................0.75
mg
Indications
The Leading Emergency Contraceptive Pill in India
Emergency Contraception consists of the administration of a
hormonal product within 72 hours after a unprotected sexual
intercourse to prevent pregnancy.
Description
Levonorgestrel belongs to the class of Progestogens, it is a
synthetic steroid and mostly used as regular oral contraception.
Levonorgestrel emergency contraceptive pills (ECPs) have been
shown to prevent ovulation and they did not have any detectable
effect on the endometrium (uterine lining) or progesterone levels
when given after ovulation. ECPs are not effective once the
process of implantation has begun, and will not cause abortion.
The few studies that have looked at levonorgestrel`s mechanisms of
action in postcoital contraception suggest that it may affect both
follicle growth and development of the corpus luteum (the
progesterone-secreting tissue that forms in the ovary immediately
after ovulation).
When 0.75 mg of Levonorgestrel administered for four days either
before ovulation, around the time of ovulation or after ovulation,
indicated that the impact of Levonorgestrel depends on the time of
administration. When Levonorgestrel was given during the early
follicular phase, the total cycle length was significantly
prolonged due to the increased duration of the follicular phase.
Post treatment biopsies taken on cycle days 20-22 still showed
proliferative endometrium in accordance with the delay in
ovulation. When levonorgestrel was administered around the time of
ovulation, the effects were variable: Ovulation was blocked in
some women, while in others follicular activity was followed by
deficient luteal function, and still other women ovulated
normally. On the other hand, administering levonorgestrel during
the luteal phase did not affect cycle length or cause any
significant endometrial changes. This last finding was somewhat
unexpected in view of the proven effectiveness of levonorgestrel
in emergency contraception.
WARNING: this method can prevent an undesired pregnancy but it
does not protect against STDs and AIDS.
Dosage
The first tablet must be taken as soon as possible after
unprotected intercourse, and within 72 hours (3 days) at the
latest after intercourse. The second tablet must be taken 12 hours
at the earliest and 24 hours at the latest after the first one.
Presentations
2 tablets
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Quality
