Emergency Contraceptive Pills, Emergency
Pill, Avoid Pregnancy
Each
film-coated tablet contains:
Composition:
Levonorgestrel I.P....................................................0.75
mg
Indications:
Emergency Contraception consists of the administration of a
hormonal product within 72 hours after a unprotected
sexual intercourse to prevent pregnancy.
Description:
Levonorgestrel belongs to the class of Progestogens, it is a
synthetic steroid and mostly used as regular oral
contraception.
Levonorgestrel emergency contraceptive pills (ECPs) have been
shown to prevent ovulation and they did not have any
detectable effect on the endometrium (uterine lining) or
progesterone levels when given after ovulation. ECPs are not
effective once the process of implantation has begun, and will
not cause abortion.
The few studies that have looked at levonorgestrel`s
mechanisms of action in postcoital contraception suggest that
it may affect both follicle growth and development of the
corpus luteum (the progesterone-secreting tissue that forms in
the ovary immediately after ovulation).
When 0.75 mg of Levonorgestrel administered for four days
either before ovulation, around the time of ovulation or
after ovulation, indicated that the impact of
Levonorgestrel depends on the time of administration.
When Levonorgestrel was given during the early follicular
phase, the total cycle length was significantly prolonged due
to the increased duration of the follicular phase.
Post treatment biopsies taken on cycle days 20-22 still showed
proliferative endometrium in accordance with the delay in
ovulation. When levonorgestrel was administered around the
time of ovulation, the effects were variable: Ovulation was
blocked in some women, while in others follicular activity was
followed by deficient luteal function, and still other women
ovulated normally. On the other hand, administering
levonorgestrel during the luteal phase did not affect cycle
length or cause any significant endometrial changes. This last
finding was somewhat unexpected in view of the proven
effectiveness of levonorgestrel in emergency contraception.
WARNING: this method can prevent an undesired pregnancy but it
does not protect against STDs and AIDS.
Dosage:
The first tablet must be taken as soon as possible after
unprotected intercourse, and within 72 hours (3 days) at the
latest after intercourse. The second tablet must be taken 12
hours at the earliest and 24 hours at the latest after the
first one.
Presentations:
1 tablets
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