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Each Tablet contains:
Cadoz Tablet
Bisoprolol Fumrate............................ 5mg
INDICATIONS:
Essential HTN, CHD (angina pectoris); as an adjunct in stable
chronic heart failure.
DOSAGE AND
ADMINISTRATION :-
Essential HTN, CHD 5 mg once daily. If effect is
inadequate, 10 mg once daily. Stable chronic heart failure
Gradually increase from 1.25 mg/day for 1 wk then 2.5 mg/day for 1
wk then 3.75 mg/day for 1 wk then 5 mg/day for the following 4 wk
& 7.5 mg/day for the following 4 wk. Maintenance: 10 mg/day. All
doses to be taken once daily.
May be taken with or without food
(Swallow whole, do not chew/ crush.)
CONTRAINDICATIONS :-
Untreated myocardial
failure, cardiogenic shock, AV block grades II & III, sick-sinus
syndrome, SA block, bradycardia w/ <50 beats/min; bronchial
asthma, hypotension, advanced stages of peripheral circulatory
disturbance; pheochromocytoma w/o concomitant α-adrenoceptor
blocker therapy. Pregnancy, lactation; childn.
SPECIAL PRECAUTIONS :-
DIabetic patients w/
greatly fluctuating blood-sugar values, during prolonged periods
of fasting; acidosis. Prior operation as cardiac output may be
impaired under anaesth. Elderly >80 yr.
ADVERSE DRUG REACTIONS :-
At start of treatment but
generally recede w/in 1-2 wk treatment: Rare: GI disturbances,
skin reactions, decreased BP, slow pulse rate, AV conduction
disturbance, cold extremities, muscle weakness/cramp & reduced
lacrimation. May aggravate intermittent claudication & Raynaud's
phenomenon, intensify myocardial failure, increase airway
resistance, impair glucose tolerance, mask signs of low sugar
levels. Fatigue, dizziness, slight headache, perspiration, sleep
disturbances, vivid dreams & depressive moods.
DRUG INTERACTIONS:-
Reserpine, α methyldopa, clonidine, guanfacine, nifedipine,
rifampicin, Ca antagonist of the verapamil & diltiazem type,
antiarrhythmics, insulin or oral blood sugar-reducing drugs.
PACKAGING INFORMATION :-
Cadoz Tablet .......................... 5mg
Presentations: 100ml |
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Quality
