Siderosis - Symptoms, Causes and Treatment
of Siderosis Noun - fibrosis of the lung caused by iron dust; occurs among
welders and other metal workers. Problems usually develop once more
than 30 g of iron accumulate. Each unit of red cells has 200 mg of
iron; normal body stores are 3-4.0 g; daily losses are 1 mg.
African siderosis is a condition of iron overload thought to be
associated with a diet high in iron. Some of the iron might be
obtained from consumption of a traditional beer drunk by several
groups of sub-Saharan Africans. The beer which is low in alcohol
is brewed in iron drums. Daily consumption of the beer may lead to
ingestion of as much as 45 to 85 milligrams of iron.
Superficial siderosis (SS) of the central nervous system is an
uncommon disease
characterized by accumulation of hemosiderin in the meninges,
brain surface, spinal cord and cranial nerves. The deposition of
hemosiderin, which may be cytotoxic to underlying tissue, results
from chronic bleeding into the subarachnoid space. In many cases,
the precise source of bleeding is not identified.
Symptoms of Siderosis
cardiac failure
growth failure in children
endocrine dysfunction - for example, diabetes mellitus
liver cirrhosis
Cause of Siderosis
Recurrent bleeding on the surface of the brain may cause
"superficial siderosis", which is typlified by bilateral
sensor neural deafness and cerebella ataxia with dysarthria and
nystagmus (Fishman, 1993). Superficial siderosis can rarely occur
as a complication of brachial plexus avulsion (Fernley et al,
1995).
Superficial siderosis can also cause bilateral vestibular loss
(Watanabe, 1997), which can cause ataxia resembling that of a
cerebellar disorder. Superficial siderosis is diagnosed through
MRI.
Treatment
This disease is only found in patients that have high or low
levels of iron in their body. Most patients that do have this
disease will only complain about high levels of iron in their
body. Siderosis is also known as the inflammation of the lungs and
this is also caused by a lot of inhaling of dust which contains
iron salts and also other iron particles. This disease is usually
a result of working with iron particles and excessively inhaling
all the iron particles can then result in your body experiencing
the symptoms of siderosis. Obviously if you are working in an
occupation that can give you high levels of iron particles then
you should have been warned about all the possible problems that
can occur with the working environment that you are in. Usually
though the only people that should worry about this disease are
workers that are welders and also other metal workers as these are
the occupations that are most at risk from contracting siderosis.
But proper protecting from these particles will reduce the risk to
zero.
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