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Pruritis |
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What is Pruritis
Pruritus is an itch or a sensation that makes a
person want to scratch. Pruritus can cause discomfort and be
frustrating. If it is severe, it can lead to sleeplessness,
anxiety, and depression. The exact cause of an itch is unknown. It
is a complex process involving nerves that respond to certain
chemicals like histamine that are released in the skin, and the
processing of nerve signals in the brain. Pruritus can be a part
of skin diseases, internal disorders, or due to faulty processing
of the itch sensation within the nervous system.
Who gets pruritus?
There are many skin diseases like urticaria (hives), varicella
(chicken pox), and eczema which may have itching associated with a
rash. Some skin conditions only have symptoms of pruritus without
having an obvious rash. Dry skin can itch, especially in the
winter, with no visual signs of a rash. Some parasitic
infestations such as scabies and lice may be very itchy. Itchy,
pigmented moles may be a sign of a malignant change.
Pruritus may be a manifestation of an internal condition. The most
common example is kidney failure. Some types of liver disease like
hepatitis, thyroid disease including both hyper (too much) and
hypo (too little) thyroid hormone levels, some blood disorders
such as lymphomas, iron deficiency anemia, polycythemia vera,
multiple myeloma, and neurologic conditions such as pinched nerves
and post herpetic neuralgia can cause itch. Infectious diseases
like HIV can cause severe itching.
How is pruritus diagnosed
and treated?
Often the dermatologist will be able to diagnose these conditions
with an examination; however, to determine a specific cause of the
itch, a blood test, skin scraping, or biopsy may be needed to help
make the diagnosis. If the itch is due to a skin disease such as
hives or eczema, treatment of the skin disease, itself, with
prescription topical medications and/or oral antihistamines
generally relieves the itch. If the itch is secondary to an
internal disease, patients may require treatment of the disease,
oral medication, or occasionally ultraviolet light therapy to
relieve the itch.
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