INDICATIONS :
1. For patients with type 2 diabetes who fail in a satisfactory
control of blood sugar level by simple alimentary control or
kinesiatrics.
2. A second-line drug for patients with type 2 diabetes who fail
in a satisfactory control of blood sugar level after the
respective treatment with sulfonylurea or deltamine.
DOSAGE AND ADMINISTRATION :
1. For patients with type 2 diabetes who fail in a satisfactory
control of blood sugar level by simple alimentary control or
kinesiatrics: 1 capsule (Glibenclamide/ dimethylbiguanide:
1.25mg/250mg) per day to be taken with a meal at the initial dose.
2. For patients with baseline HbAlc>9% or FPG>200md/dl and treated
for the first time: The initial dose is 1 capsule (Glibenclamide/
dimethylbiguanide: 1.25mg/250mg) to be taken with breakfast and
supper twice daily at the initial dose; Increasing daily dose
every two weeks to achieve the minimum effective dose.
3.
For patients who have taken other hypoglycemic agents: 2 capsules
(Glibenclamide/ dimethylbiguanide: 2.5mg/500mg) or 4 capsules (Glibenclamide/
dimethylbiguanide: 5mg/1000mg) to be taken with meals twice daily
at the initial dose. For patients who fail in a satisfactory
control of blood sugar level after the respectvie treatment of
sulfonylurea or deltamine: 2 capsules (Glibenclamide/
dimethylbiguanide: 2.5mg/500mg) or 4 capsules (Glibenclamide/
dimethylbiguanide: 5mg/1000mg) to be taken with meals twice daily
at the initial dose. To avoid glycopenia, the initial dose should
not exceed the daily dose of sulfonylurea or deltamine taken
before. Daily dose should be adjusted step by step, increment per
time should be no more than 2 capsules (Glibenclamide/
dimethylbiguanide: 2.5mg/500mg) to achieve the minimum effective
therapeutic dose.
4.The maximum daily dose should not exceed 8 capsules (Glibenclamide/
dimethylbiguanide: 10mg/2000mg).
SPECIFICATION :
0.25g dianoguanil and 1.25mg Glybenzcyclamide per capsule
STORAGE:
Keep tightly closed at the room temperature. Protect from direct
light.
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