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Bisoprolol Fumrate Tablet
Bisoprolol Fumrate............................ 5mg
INDICATIONS:
Essential HTN, CHD (angina pectoris); as an adjunct in stable
chronic heart failure.
DOSAGE
AND ADMINISTRATION :
Essential HTN, CHD 5 mg once daily. If effect is inadequate, 10 mg
once daily. Stable chronic heart failure Gradually increase from
1.25 mg/day for 1 wk then 2.5 mg/day for 1 wk then 3.75 mg/day for
1 wk then 5 mg/day for the following 4 wk & 7.5 mg/day for the
following 4 wk. Maintenance: 10 mg/day. All doses to be taken once
daily.
May be taken with or without food (Swallow whole, do not chew/
crush.)
CONTRAINDICATIONS :
Untreated myocardial failure, cardiogenic shock, AV block grades
II & III, sick-sinus syndrome, SA block, bradycardia w/ <50
beats/min; bronchial asthma, hypotension, advanced stages of
peripheral circulatory disturbance; pheochromocytoma w/o
concomitant α-adrenoceptor blocker therapy. Pregnancy, lactation;
childn.
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SPECIAL PRECAUTIONS :
DIabetic patients w/ greatly fluctuating blood-sugar values,
during prolonged periods of fasting; acidosis. Prior operation as
cardiac output may be impaired under anaesth. Elderly >80 yr.
ADVERSE DRUG REACTIONS :
At start of treatment but generally recede w/in 1-2 wk treatment:
Rare: GI disturbances, skin reactions, decreased BP, slow pulse
rate, AV conduction disturbance, cold extremities, muscle
weakness/cramp & reduced lacrimation. May aggravate intermittent
claudication & Raynaud's phenomenon, intensify myocardial failure,
increase airway resistance, impair glucose tolerance, mask signs
of low sugar levels. Fatigue, dizziness, slight headache,
perspiration, sleep disturbances, vivid dreams & depressive moods.
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DRUG INTERACTIONS :
Reserpine, α methyldopa, clonidine, guanfacine, nifedipine,
rifampicin, Ca antagonist of the verapamil & diltiazem type,
antiarrhythmics, insulin or oral blood sugar-reducing drugs.
PACKAGING INFORMATION :
Bisoprolol Fumrate Tablet .......................... 5mg
Wallpapers :
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