Lymphogranuloma venereum (LGV) is a
sexually transmitted bacterial infection.
Causes
Lymphogranuloma venereum (LGV) is a chronic (long-term) infection
of the lymphatic system caused by three different types of the
bacteria Chlamydia trachomatis. The bacteria spread through sexual
contact. The infection is caused by a different bacteria than that
which causes genital chlamydiachlamydia.
LGV is more common in Central and South America than in North
America. Every year, a few hundred cases of LGV are diagnosed in
the United States. However, the actual number of infections is
unknown.
LGV is more common in men than women. The main risk factor is
having multiple sexual partners.
Symptoms
Symptoms of LGV can begin a few days to a month after coming in
contact with the bacteria. Symptoms include:-
Small painless ulcer on the male genitalia or in the female
genital tract
Swelling and redness of the skin in the groin area
Swollen groin lymph nodes on one or both sides; it may also affect
lymph nodes around the rectum in those who have anal intercourse
Drainage through the skin from lymph nodes in groin
Blood or pus from the rectum (blood in the stoolsblood in the
stools)
Painful bowel movements (tenesmustenesmus)
Swelling of the labia
The infection can cause diarrhea and lower abdominal pain. Women
may develop abnormal connections called fistulas between the
vaginavagina and rectum.
Exams and Tests
The health care provider will perform a physical
examinationphysical examination and ask questions about your
medical history. It is important to tell your doctor if you had
sexual contact with someone who has had lymphogranuloma venereum.
A physical exam may show:-
An ulcer on the genitals
An oozing, abnormal connection (fisula) in the rectal area
Swollen lymph nodes in the groin (inguinal
lymphadenopathylymphadenopathy)
Drainage through the skin from lymph nodes in the groin
Swelling of the vulva or labia in women
Tests may include:-
BiopsyBiopsy of the lymph node
Blood test for the bacteria that causes LGV
Laboratory test to detect chlamydia
Treatment
This condition can be cured with the proper antibiotics. Those
commonly prescribed to treat LGV include tetracycline, doxycycline,
and erythromycin.
Outlook (Prognosis)
With treatment, the outlook is good.
Possible Complications
Abnormal connections between the rectum and vagina
Brain inflammation (very rare)
Infections in the joints, eyes, heart, or liver
Long-term inflammation and swelling of the genitalia
Scarring and narrowing of the rectum
Complications can occur many years after the initial infection.
When to Contact a Medical Professional
Call your health care provider if you have been in contact with
someone who may a sexually transmitted disease, including LVG.
Also call if symptoms of LVG develop.
Prevention
Abstaining from sexual activity is the only absolute way to
prevent a sexually transmitted disease. Safer sex behaviors may
reduce the risk.
The proper use of condoms, either the male or female type, greatly
decreases the risk of catching a sexually transmitted disease. You
need to wear the condom from the beginning to the end of each
sexual activity.
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