Gardner Syndrome is a rare,
hereditary disorder involving the colon. It is characterized by
multiple growth (polyps) in the colon but affected patients also
develop bone and soft tissue tumors. Symptoms of Gardner Syndrome
generally appear during the teen years. They may include extra
teeth (supernumerary), bony tumors of the skull (osteomas), and
fatty cysts or fibrous tumors in the skin (fibromas or epithelial
cysts). Individuals affected with Gardner Syndrome may also
experience painless rectal bleeding and abdominal cramping.
Complications include bowel obstruction and rectal prolapse and/or
the growth of other tumors in the GI (gastrointestinal) tract.
Treatment of Gardner Syndrome involves close observation of the
patient to monitor growths of the polyps and tumors. A colonoscopy
is repeatedly performed to remove the polyps after the onset of
the disease. Removal of the colon and rectum is often necessary
once the disease has progressed to more advanced stages.
Gardner’s Syndrome is inherited as an autosomal dominant trait; a
person who carries the gene for Gardner’s Syndrome will eventually
develop the disease. Genetic counseling is strongly recommended to
anyone with a family history of this disease. A new test is now
available to couples who are at risk of passing the disease on to
their child. Pre-Implantation Genetic Diagnosis (PGD) examines the
embryos created through IVF for genetic defects such as the
Gardner Syndrome gene. Only embryos that do not contain the
defective gene are implanted into the mother. This give couples
the assurance that they will not pass on a debilitating disease to
their children.
Gardner Syndrome generally appear during the teen
years
Remove Tumor From
Gardner's Syndrome Patient
Gardner Syndrome may also experience painless
rectal bleeding
Gardner Syndrome - treatment of Gardner
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