Duchenne Muscular Dystrophy (DMD)
is an X-linked disorder that is characterized by progressive
muscle weakness and other associated complications. It affects
approximately one out of 3,500 males, regardless of ethnic or
socioeconomic background. Around the age of five years, affected
boys begin to stumble and fall more than is normal. They also
generally show a change in posture and often walk on their toes.
Some boys with DMD may also experience learning difficulties and
may be mildly retarded.
Muscle weakness progresses over time and in some cases, wheelchair
use is necessary by the age of thirteen. Complications associated
with DMD include breathing difficulties, scoliosis (abnormal
curvature of the spine), and heart problems. During the end stages
of DMD, the entire body weakens, and the disease involves
practically every system of the body. Affected individuals
generally die by the age of twenty years, mainly due to severe
lung problems or heart failure.
Currently, there is no cure for DMD, but treatments are available
for the symptoms. Physiotherapy is available to help strengthen
the muscle and to alleviate muscle pain. Inhalants, antibiotics
and other medications are also available to ease respiratory
problems. Steroid treatment of DMD remains controversial, but is
an option. Gene therapy, such as myoblast transfer, is being
explored as a possible treatment for DMD.
Although the majority of DMD cases are inherited, about one third
of cases of DMD are caused by sporadic and random gene mutation.
The chance that a woman with an affected son, apparently due to a
sporadic gene mutations, will have another affected son or a
daughter who is a carrier is increased. Any family with a history
of DMD is strongly encouraged to seek genetic counseling.
Couples now have the option to take advantage of a new test called
Pre-Implantation Genetic Diagnosis (PGD). PGD tests for genetic
defects, such as the Duchenne Muscular Dystrophy gene, in embryos
conceived through IVF. Only healthy embryos are implanted and
parents are assured that their children will not inherit or be a
carrier for this disease.
Treatment of Duchenne muscular dystrophy
Duchenne muscular
dystrophy, disuse atrophy, ageing and muscle regeneration
following injury/surgery
Voluntary muscles are
affected by Duchenne MD
Duchenne Muscular Dystrophy - treatment of
Duchenne Muscular Dystrophy, Duchenne Muscular Dystrophy types, Disease
medicines, Duchenne Muscular Dystrophy symptoms, Duchenne Muscular Dystrophy
and Disease symptoms, Duchenne Muscular Dystrophy symptoms Disease and
diagnosis, Symptoms and Solutions, Signs and Symptoms, type of Duchenne
Muscular Dystrophy, cause common, common Duchenne Muscular Dystrophy,
Duchenne Muscular Dystrophy List, causes list, Infectious Duchenne Muscular
Dystrophy, Causes, Diseases , Types, Prevention, Treatment and Facts,
Duchenne Muscular Dystrophy information, Duchenne Muscular Dystrophy:
Definition, Duchenne Muscular Dystrophy names, medical Duchenne Muscular
Dystrophy, medical Duchenne Muscular Dystrophy and disorders, cell Duchenne
Muscular Dystrophy, Duchenne Muscular Dystrophy Worldwide, Duchenne Muscular
Dystrophy Research, Duchenne Muscular Dystrophy Control, Duchenne Muscular
Dystrophy Center, Digestive Duchenne Muscular Dystrophy Week, Information
about Duchenne Muscular Dystrophy, causes of different Duchenne Muscular
Dystrophy, Duchenne Muscular Dystrophy Articles, Duchenne Muscular Dystrophy
and conditions, Health and Duchenne Muscular Dystrophy, Duchenne Muscular
Dystrophy Patients, Duchenne Muscular Dystrophy and Sciences, causes of
alzheimer's Duchenne Muscular Dystrophy, Duchenne Muscular Dystrophy causes,
alternative medicine heart Duchenne Muscular Dystrophy, body ailments,
Duchenne Muscular Dystrophy medicines, medical antiques, type of blood
Duchenne Muscular Dystrophy