Brufade (deferasirox) binds to
iron and removes it from the blood stream. Brufade is used to
treat iron overload caused by blood transfusions in adults and
children at least 2 years old.
BRUFADE is a tridentate ligand that binds iron with high
affinity, forming a 2:1 complex that is excreted in bile and
eliminated primarily via the feces.
BRUFADE is indicated for the treatment of chronic iron overload
due to frequent blood transfusions (≥7 ml/kg/month of packed red
blood cells) in patients with beta thalassemia major aged 6
years and older.
BRUFADE is also indicated
for the treatment of chronic iron overload due to blood
transfusions when deferoxamine therapy is contraindicated or
inadequate in the following patient groups:
in
patients with beta thalassemia major with iron overload due
to frequent blood transfusions (≥7 ml/kg/month of packed red
blood cells) aged 2 to 5 years
in
patients with beta thalassemia major with iron overload due
to infrequent blood transfusions (<7 ml/kg/month of packed
red blood cells) aged 2 years and older
in
patients with other anemias aged 2 years and older
BRUFADE is also indicated for the
treatment of chronic iron overload requiring chelation therapy
when deferoxamine therapy is contraindicated or inadequate in
patients with non−transfusion−dependent thalassemia syndromes
aged 10 years and older.
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Note :This product information is intended only for
residents of the India. Taj Pharmaceuticals Limited,
medicines help to treat and prevent a range of conditions—from the
most common to the most
challenging—for people around the world.
Information for Health Care Professionals
*** Please consult local Prescribing
Information for any product before use. This website is an
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professionals with an interest in disease management. This
website is not intended to replace the advice of a
qualified healthcare professional. Above brand is a
trademark of the Taj group of companies (Taj
Pharmaceuticals Limited).
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