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ZIDROK does not cure HIV infection/AIDS
or prevent passing HIV to others. ZIDROK in combination with other
HIV medicines is indicated for the treatment of HIV infection.
HIV is the human immunodeficiency virus. It causes AIDS.
ZIDROK slows HIV from making more copies of itself. This can keep
the virus from infecting new cells. It can lower the amount of HIV
in your body. Your CD4 cell count can increase with the lowering
of the HIV virus.
The two drugs together are stronger against the virus than either
one alone. ZIDROK should be taken with other HIV drugs.
ZIDROK can be part of many treatments now used to fight HIV.
Composition
lamivudine and zidovudine
Each tablet contains
lamivudine ........... 250 mg
zidovudine...... 300 mg
Important Safety Information for ZIDROK
Possible Side Effects of ZIDROK
It’s important to know that serious side effects can occur with
ZIDROK, such as a decrease in red and white blood cells and muscle
damage. A buildup of lactic acid and an enlarged liver, including
fatal cases, have been reported rarely with some HIV drugs,
including nucleoside analogues.
For HIV-infected individuals, periodic blood tests are
recommended. If certain changes occur in your laboratory results
while you are taking ZIDROK, particularly if you become anemic or
if your white blood cell count falls too low, your medication may
need to be adjusted; your doctor may prescribe EPIVIR plus
RETROVIR separately in place of ZIDROK.
Some patients infected with both hepatitis B virus (HBV) and HIV
have worsening of hepatitis after stopping lamivudine (a component
of ZIDROK). Discuss any change in treatment with your doctor. If
you have both HBV and HIV and stop treatment with ZIDROK, you
should be closely monitored by your doctor for at least several
months.
Worsening of liver disease (sometimes resulting in death) has
occurred in patients infected with both HIV and hepatitis C virus
who are taking anti-HIV medicines and are also being treated for
hepatitis C with interferon with or without ribavirin. If you are
taking ZIDROK as well as interferon with or without ribavirin and
you experience side effects, be sure to tell your doctor.
When you start taking HIV medicines, your immune system may get
stronger and could begin to fight infections that have been hidden
in your body, such as pneumonia, herpes virus or tuberculosis. If
you have new symptoms after starting your HIV medicines, be sure
to talk with your doctor.
Changes in body fat may occur in some patients taking
antiretroviral therapy. These changes may include an increased
amount of fat in the upper back and neck (“buffalo hump”), breast,
and around the trunk. Loss of fat from the legs, arms and face may
also occur. The cause and long-term health effects of these
conditions are not known at this time.
In clinical studies of lamivudine plus zidovudine, side effects
occurring in 5% or more of patients included: headache, upset
stomach, weakness and fatigue, and nasal symptoms.
Tell your doctor promptly about any side effects or other unusual
symptoms you may experience. Although it may make you healthier,
ZIDROK does not cure HIV.
Indication and Usage
ZIDROK does not cure HIV infection/AIDS or prevent passing HIV to
others. ZIDROK in combination with other HIV medicines is
indicated for the treatment of HIV infection.
Presentation
ZIDROK KIT
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