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Each kit contains
Composition
1 cap of Rifampicin..............................................450
mg
1 Tab of Ethambutol............................................800
mg
1 Tab of INH..........................................................150
mg
Indications
Rifampicin, Ethambutol, Isoniazid, Pyrazinamide and Streptomycin
are used in medication and management of Tuberculosis.
Description
Rifampicin inhibits DNA-dependent RNA polymerase in bacterial
cells by binding its beta subunit, thus preventing transcription
of messenger RNA (mRNA) and subsequent translation to proteins.
Ethambutol is a synthetic, bacteriostatic antitubercular agent.
Ethambutol diffuses into actively growing mycobacteria cells such
as tubercle bacilli . It appears to inhibit the synthesis of one
or more metabolites, thus impairing cell metabolism, arresting
multiplication, and resulting in cell death.
INH is thought to work through its effects on lipids (fats) and
DNA within the tuberculosis bacterium.
Dosage
Adults: (below 50 kg) : 450 mg daily as a single dose. More than
50 kg : upto 600 mg daily.
Presentations
1 kit
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