Each Injection
contains:
Composition:
Inj. Ondansetron
2ml Amp..............................................2mg /ml
Indications:
Emetron helps to
relieve nausea and vomiting, especially when associated with the
treatment of cancer (chemotherapy). Ondansetron may also be used
to prevent or treat nausea and vomiting that occurs after surgery,
and occasionally is used to treat severe vomiting during
pregnancy.
Description:
Ondansetron is a
competitive, highly selective antagonist of 5-hydroxytryptamine
(serotonin) subtype 3 (5-HT 3) receptors. 5-HT 3
receptors are present peripherally on vagal nerve terminals
centrally in the area postrema of the brain. It is not certain
whether ondansetron's action is mediated peripherally, centrally,
or both. Cytotoxic drugs and radiation appear to damage
gastrointestinal mucosa, causing the release of serotonin from the
enterochromaffin cells of the gastrointestinal tract. Stimulation
of 5-HT 3 receptors causes transmission of sensory
signals to the vomiting center via vagal afferent fibers to induce
vomiting. By binding to 5-HT 3 receptors, ondansetron
blocks vomiting mediated by serotonin release.
Ondansetron has no dopamine-receptor antagonist activity.
Dosage :
As per the physician’s advice.
Presentations
:
2 ml |
Quality
