Generic Name:
aspirin
Brand Name:
REXPRIN
Tablets
REXPRIN
75mg
film-coated tablets
REXPRIN
100mg
film-coated tablets
Active ingredients: ACETYLSALICYLIC ACID
PHARMACOLOGICAL ACTION:
Aspirin helps prevent the formation of blood clots.
This can decrease the chance that a blood clot will
form and block an already-narrowed artery.
Usage :
Aspirin may be given to people who have peripheral
arterial disease (PAD) or risk factors for
peripheral arterial disease. It may also be used
after bypass surgery or angioplasty to
prevent the formation of blood clots after these
procedures.
How Well It Works
Research results vary on the effects of aspirin for
PAD, but it may lower the risk for heart attack and
stroke.
Side Effects
Side effects of aspirin include:
-
Inflammation of the stomach (gastritis).
-
Gastrointestinal bleeding.
-
An allergic reaction.
-
In rare cases, bruising and bleeding
(hemorrhage) in the brain or other internal
organs of the body.
Contraindications
Exacerbation phase of erosive-ulcerative lesions in
the gastrointestinal tract, gastro-intestinal
bleeding, "aspirin triad", a history of indications
urticaria, rhinitis, caused by taking aspirin and
other NSAIDs, hemophilia, hemorrhagic diathesis,
gipoprotrombinemii, dissecting aneurysm of the
aorta, portal hypertension, deficiency of vitamin K,
liver and / or renal failure, deficiency of
glucose-6-phosphate dehydrogenase, Reye syndrome,
children's age (under 15 years - the risk of
developing Reye syndrome in children with
hyperthermia on a background of viral diseases), I
and III trimester of pregnancy, lactation,
hypersensitivity to aspirin and other salicylates.
What To Think About:
Aspirin may be combined with other antiplatelet or
anticoagulant medicines.
Some doctors are concerned that long-term daily
aspirin use can increase the risk of stomach
problems. A smaller dose, such as a single low-dose
aspirin, is often used and appears to be just as
effective as a higher dose. Consult your doctor
before you start taking aspirin on a regular basis.
Because of aspirin's effect on blood clotting, your
doctor may want you to stop your aspirin at least 5
to 10 days before surgery and before any dental
procedure that may cause excessive bleeding.
Using during pregnancy and breastfeeding
Aspirin (acetylsalicylic acid) is contraindicated in
I and III trimester of pregnancy. In pregnancy
trimester II can a one-off reception on the strict
condition.
This medication has a teratogenic effect: when used
in the I trimester leads to top palatoschisis, in
the III trimester - cause inhibition of labor
(inhibition of prostaglandin synthesis), premature
closure of the ductus arteriosus in the fetus,
pulmonary vascular hyperplasia and hypertension in
the pulmonary circulation.
aspirin (acetylsalicylic acid) is excreted in breast
milk, which increases the risk of bleeding in a
child due to dysfunction of platelets, and therefore
should not be applied acetylsalicylic acid in the
mother during lactation.
Precautionary measures
Undesirable combined use with other NSAIDs and
glucocorticoids. For 5-7 days before surgery should
stop taking (to reduce bleeding during surgery and
postoperative period).
The probability of NSAID-gastropathy decreases in
the appointment after a meal, use of tablets with
buffer additives or coated with a special
enteric-soluble shell. The risk of hemorrhagic
complications is minimal when used in doses less
than 100 mg / day.
Note that in predisposed patients acetylsalicylic
acid (even in small doses) reduces the excretion of
uric acid from the body and can cause the
development of acute attack of gout.
During prolonged therapy should regularly carry out
the analysis of blood and to investigate faeces for
occult blood. In connection with the observed cases
hepatogenic encephalopathy is not recommended for
relief of fever syndrome in children.
Supplied: REXPRIN
is supplied
in the form of 75mg, 100mg tablets.
STORAGE:
Should be stored at room temperature,
20-25 C (68-77 F), in a sealed container, avoiding
moisture.
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