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ORGALOX is
A PRESCRIPTION MEDICINE USED WITH OTHER MEDICINES TO HELP PREVENT ORGAN REJECTION IN PEOPLE WHO HAVE HAD A KIDNEY, LIVER, OR HEART TRANSPLANT.

ORGALOX IS A PRESCRIPTION MEDICINE USED WITH OTHER MEDICINES TO HELP PREVENT ORGAN REJECTION IN PEOPLE WHO HAVE HAD A KIDNEY, LIVER, OR HEART TRANSPLANT. ORGALOX IS NOT FOR USE WITH MEDICINES CALLED CYCLOSPORINES (GENGRAF®, NEORAL®, AND SANDIMMUNE®) AND IS NOT FOR USE WITH A MEDICINE CALLED SIROLIMUS (RAPAMUNE®) IN PEOPLE WHO HAVE HAD A LIVER OR HEART TRANSPLANT. IT IS NOT KNOWN IF ORGALOX IS SAFE AND EFFECTIVE WHEN USED WITH SIROLIMUS IN PEOPLE WHO HAVE HAD KIDNEY TRANSPLANTS. IT IS NOT KNOWN IF ORGALOX IS SAFE AND EFFECTIVE IN CHILDREN WHO HAVE HAD KIDNEY OR HEART TRANSPLANTS.

What is the most important information I should know about ORGALOX?
ORGALOX can cause serious side effects, including:
1. Increased risk of cancer. People who take ORGALOX have an increased risk of getting some kinds of cancer, including skin and lymph gland cancer (lymphoma).
2. Increased risk of infection. ORGALOX is a medicine that affects your immune system. ORGALOX can lower the ability of your immune system to fight infections. Serious infections can happen in people receiving ORGALOX that can cause death. Call your doctor right away if you have symptoms of an infection such as fever, sweats or chills, cough or flu‐like symptoms, muscle aches, and/or warm, red, or painful areas on your skin.
Do not take ORGALOX if you are allergic to tacrolimus or any of the ingredients in ORGALOX.
What should I tell my doctor before taking ORGALOX?
Before you take ORGALOX, tell your doctor if you: plan to receive any live vaccines, have or have had liver, kidney or heart problems, are pregnant or plan to become pregnant Talk to your doctor if you are pregnant or plan to become pregnant. Tell your doctor if you are breastfeeding or plan to breastfeed. ORGALOX can pass into your breast milk. You and your doctor should decide if you will take ORGALOX or breastfeed. You should not do both.
Tell your doctor about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements. Especially tell your doctor if you take: cyclosporine (Gengraf®, Neoral®, and Sandimmune®), sirolimus (Rapamune®), nelfinavir (Viracept®), telaprevir (Incivek®), boceprevir (Victrelis®) or amiodarone (Cordarone®, Nexterone®, Pacerone®). ORGALOX may affect the way other medicines work, and other medicines may affect how ORGALOX works. Know the medicines you take. Keep a list of your medicines and show it to your doctor and pharmacist when you get a new medicine.
How Should I Take ORGALOX?
Do not eat grapefruit or drink grapefruit juice while taking ORGALOX. Take ORGALOX exactly as your doctor tells you to take it. Take ORGALOX with or without food and the same way and time every day. If you take too much ORGALOX, call your doctor or go to the nearest hospital emergency room right away.
ORGALOX may cause serious side effects, including:
• high blood sugar (diabetes). Your doctor may do certain tests to check for diabetes.
• kidney problems. Your doctor may do certain tests to check your kidney function.
• nervous system problems
• high levels of potassium in your blood. Your doctor may do certain tests to check your potassium level.
• high blood pressure. Your doctor will monitor your blood pressure.
• heart problems (myocardial hypertrophy)
Call your doctor right away if you have any of these symptoms: frequent urination, increased thirst or hunger, blurred vision, confusion, drowsiness, loss of appetite, fruity smell on your breath, nausea, vomiting, stomach pain, muscle tremors, numbness and tingling, headache, seizures, coma, vision changes, shortness of breath, chest pain, feel lightheaded, or feel faint.

Orgalox is an immunosuppressive drug used mainly after allogeneic organ transplant to lower the risk of organ rejection. It achieves this by inhibiting the production of interleukin-2, a molecule that promotes the development and proliferation of T cells, which are vital to the body's learned (or adaptive) immune response. Tacrolimus is also used in the treatment of other T cell-mediated diseases such as eczema (for which it is applied to the skin in a medicated ointment), severe refractory uveitis after bone marrow transplants, exacerbations of minimal change disease, Kimura's disease, and the skin condition vitiligo.

The most common side effects of ORGALOX are: tremors (shaking of the body); high blood pressure; kidney problems; diarrhea; headache; stomach pain; trouble sleeping; nausea; pain; weakness or low red blood cell count (anemia); infection; constipation; low levels of phosphate in your blood; swelling of the hands, ankles, or legs; high levels of fat or potassium in your blood; numbness or tingling in your hands or feet; fever; or low levels of magnesium in the blood.
Tell your doctor if you have any side effect that bothers you or that does not go away. These are not all the possible side effects of ORGALOX. For more information, ask your doctor or pharmacist. Call your doctor for medical advice about side effects.

orgalox is available for oral administration as capsules (tacrolimus capsules USP) containing the equivalent of 0.5 mg, 1 mg or 5 mg of anhydrous tacrolimus USP.

PACKING: 10 CAPSULES PER ALU - ALU BLISTER / 500 CAPSULES
Sterile solution (tacrolimus injection) - 5 mL

SPECIAL DISCOUNTED PRICES FOR NGO / HOSPITALS .


tacrolimus

Note :
This product information is intended only for residents of the India. Taj Pharmaceuticals Limited,  medicines help to treat and prevent a range of conditions—from the most common to the most challenging—for people around the world.

Information for Health Care Professionalstacrolimus
*** Please consult local Prescribing Information for any product before use. This website is an international information resource for healthcare professionals with an interest in disease management. This website is not intended to replace the advice of a qualified healthcare professional. Above brand is a trademark of the Taj group of companies (Taj Pharmaceuticals Limited).

 

 

 

 

Prescription medicine used with other medicines to help prevent organ rejection .

  Ogralox ® (tacrolimus)
 Prescription Products (Rx)
 
tacrolimus


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Tacrolimus capsules, USP


              
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