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Each film-coated tablet contains
Composition
Paracetamol I.P................................................325
mg
Ibuprofen I.P.....................................................200
mg
Caffeine I.P........................................................40
mg
Excipients..............................................................q.s.
Indications
For fast relief from Headache, Toothache, Muscular ache, pain,
Cold Symptoms and Feverish conditions.
Description
Paracetamol (called acetaminophen in the USA) is a derivative of
p-aminophenol, which corresponds to the active principal
metabolite phenacetin.
Its mechanism of action is not clearly established. It appears
that paracetamol inhibits prostaglandin biosynthesis in the
central nervous system but not (or hardly) in the peripheral
tissues. In any case, paracetamol only has minimal
anti-inflammatory action compared to non-steroidal
anti-inflammatory agents.
Contraindications
Paracetamol should not be used in hypersensitivity to the
preparation and in severe liver diseases.
Special warnings and precautions
The preparation should be used with care in patients with liver
and renal diseases. The treatment with Paracetamol may change the
laboratory tests of uric acid and blood glucose analysis. In
severe renal failure the interval between two consecutive takings
should not be shorter than 8 hours. The treatment with the
preparation is not advisable during the first trimester of the
pregnancy. In nursing women the preparation should be used with
strictly observation of the therapeutic dose and duration of the
treatment.
Dosage
1-2 Tablets 3 t o 4 times daily. In accordance with age or as
directed by the Physician.
Presentations
10 tablets
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Quality
