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Composition
Dopin Tablets
Each tablet contains Dothiepin hydrochloride ..........5mg
Indications
Depression. Anxiety associated with depression.
Dosage and Administration
Adults: Initially 75mg daily in divided doses or as a single dose
at night. Increasing to 150 mg with caution & under close
supervision. Maintanence: 150 mg as a single dose at night.
Children: Not recommended.
Interactions
Anticholinergics: Enhanced effect of anticholinergics may occur.
Barbiturates: Serum level of imipramine decreased; additive
respiratory depressant effect. Clonidine: Hypertensive crisis.
Dicoumarol: Increase in anticoagulation effects. Disulfiram: Acute
organic brain syndrome. Fluoxetine & Haloperidol: Potentiate
action of imipramine. Levodopa: Its bioavailability is reduced,
hypertensive episodes. MAOIs, Furazolidone: Seizures, sweating,
coma, hyperexcitability, hyperthermia, tachycardia, mydriasis,
confusion, DIC. (Disseminated Intravascular Coagulation) and
death. Oral Contraceptives and Phenothiazines: Increase plasma
levels of imipramine. Smoking: Increases metabolic
bio-transformation. Alcohol: Sedative effect of alcohol
potentiated.
Warnings and precautions
Should be take by on the prescription of a registered medical
practitioner only.
Presentation
Dopin Blister pack of 30 tablets |
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Quality
